Palmetto Harmony CBD Oil Review

Company Overview

Palmetto Synergistic Research LLC manufactures the CBD product line Palmetto Harmony. Founded in 2015, the company is located in Conway, South Carolina.

Janel Ralph is the company’s founder. Janel’s daughter Harmony is the inspiration behind the brand’s name. Palmetto is Harmony’s birth state.

Harmony has lissencephaly. It’s a rare genetic neurological condition also referred to as “smooth brain.” Severe seizures are a common symptom. Janel used CBD oil to reduce Harmony’s seizures. They also managed to reduce her reliance on pharmaceuticals by 90%.

Their hemp comes from Kentucky. It is organically grown. They use combative pests instead of chemicals as pesticides. Their product line includes organic hemp oil, capsules, topicals, vapes, and pet products. All products are third-party tested by an ISO certified lab.

Company Mission

“Palmetto Harmony strives to be the leading industry provider of all natural essential life oils, cultivated with only organic practices.”



Palmetto Harmony is made with pharmaceutical grade MCT and oil extracted from the hemp. 20mg CBD in 3.4oz (100ml) or 1oz (30ml) bottle.


Capsules and suppositories made with full spectrum hemp oil, antioxidants, and omega 3,6, and 9 fatty acids. 10mg CBD per capsule/suppository. Capsules are available in 30-count and 60-count. Suppositories come in a package of seven.

Pet Products

Palmetto Paws is made with infused whole plant extract into fractionated coconut oil (MCT). No artificial flavoring or additives.  20mg CBD in 0.5oz (15ml) and 1oz (30ml) bottle.


Palmetto Aura Vape Oil – Made with 100% VG Whole plant full spectrum oil. Contains no PG, flavoring, chemicals, or CBD Crystalline. Available in 10mg CBD in 0.5oz (15ml) and 1oz (30ml) bottle.

Palmetto Harmony Vaporizer Device – Ceramic coil vape pen pre-filled with Palmetto Aura Vape Oil. Pre-filled vape cartridges are also avaiable and are sold seperately for use with the vaporizer device.


Palmetto Harmony Transdermal Patch – 30mg CBD per patch. Ingredients include hemp cannabis extract, menthol, camphor, methyl salicylate, mineral oil, and oleic acid.

Cannacense – 2oz jar of topical cream. Ingredients include CBD Hemp Oil, Organic East African Shea Butter, Beeswax, Frankincense, and  Lemon.

Holy Cannacense – 2oz jar of topical cream. Ingredients include CBD Hemp Oil, Organic East African Shea Butter, Beeswax, Holy Basil, Frankincense, and Sweet Orange.

Psorian Cream – 2oz jar of topical cream. Ingredients include CBD Hemp Oil, Organic East African Shea Butter, Beeswax, Gotu Kola, Comfrey Root, Calendula, Marshmallow Root, and Lavender.

Customer Service

  • Telephone number – 843-331-1246
  • Service hours – Monday – Friday, 9 a.m. – 5 p.m. EST
  • Email – [email protected]

Customer Reviews

“I have been taking CBD hemp oil for almost a month. I started taking it for leg spasms from MS. The leg spasms are much better. I have had days without any spasms. Other days I have had some but they are not nearly as intense and the duration is much shorter. I gave it 4 stars because I still have spasms but my head says it should be 5 because my quality of life has improved noticeable. I am more active then I have been in a long time. My quality of life is definitely better.” – J Morriss

“Amazing company, amazing product. Customer service is the absolute best. The product speaks for itself and has changed my life.” – R. Hart

“My daughter has been completely seizure free due to Palmetto Harmony. We’ve even been able to wean from medications. It has been our saving grace.” – J. McIntyre

“Best customer service. I ordered a small bottle of Palmetto Harmony approximately one month ago to help my child who has absence seizures. This product has been a life changer at our house. We are seeing many seizure free days and more energy. I just made my second order!” – Kara

“This oil is helping me manage systemic inflammation from Lyme disease. Thank you!” – Meredith



  • Ship to all 50 states
  • Free phone consultations with medical professional


  • Third-party lab tests available on request only
  • No international shipping


Palmetto Harmony is a labor of love for the Ralph family. It’s a family run business and they do their best to treat their customers as part of the family as well.

Customer reviews show that their customer service is exceptional. They are accessible via phone, email or social media. Customers also like the free medical consultation option.